In Vitro Investigation, Pharmacokinetics, and Disposition of Imeglimin, a Novel Oral Antidiabetic Drug, in Preclinical Species and Humans

Author:

Clémence Chevalier,Fouqueray Pascale,Sébastien Bolze

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference19 articles.

1. BIOCHEMICAL, CELLULAR, AND PHARMACOLOGICAL ASPECTS OF THE MULTIDRUG TRANSPORTER

2. CDER (2020b) Guidance for industry: in vitro drug interaction studies — cytochrome P450 enzyme- and transporter-mediated drug interactions.

3. CDER (2020a) Guidance for industry: clinical drug interaction studies — cytochrome p450, enzyme- and transporter-mediated drug interactions.

4. Center for Drug Evaluation and Research (CDER) (2020c) Guidance for industry: Safety testing of drug metabolites. U.S. Department of Health and Human Services, Food and Drug Administration, Rockville, MD

5. Chevalier C Perrimond-Dauchy S Dubourg J Fouqueray P Bolze S (2020) Lack of drug-drug interaction between cimetidine, a renal transporter inhibitor, and imeglimin, a novel oral antidiabetic drug, in healthy volunteer. Eur J Drug Metab Pharmacokinet DOI: 10.1007/s13318-020-00642-4 [published ahead of print].

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