Simplifying the Execution of HepatoPac MetID Experiments: Metabolite Profile and Intrinsic Clearance Comparisons-Reference-Cited by-同舟云学术

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Simplifying the Execution of HepatoPac MetID Experiments: Metabolite Profile and Intrinsic Clearance Comparisons

Published:2020-07-04 Issue:9 Volume:48 Page:804-810
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ballard T. Eric,Kratochwil N.,Cox Loretta M.,Moen Mark A.,Klammers F.,Ekiciler A.,Goetschi A.,Walter I.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference22 articles.

1. Genetic factors influencing the metabolism of tolbutamide

2. Generation of Major Human Excretory and Circulating Drug Metabolites Using a Hepatocyte Relay Method

3. Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism

4. Determination of Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds: Comparison of a Primary Hepatocyte/Stromal Cell Co-culture with Plated Primary Hepatocytes and HepaRG

5. Assessment of the Biotransformation of Low-Turnover Drugs in the HµREL Human Hepatocyte Coculture Model

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