Recent advances in measurement of metabolic clearance, metabolite profile and reaction phenotyping of low clearance compounds
Author:
Affiliation:
1. Research Fellow, Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, CT, USA
Funder
not funded
Publisher
Informa UK Limited
Subject
Drug Discovery
Link
https://www.tandfonline.com/doi/pdf/10.1080/17460441.2023.2238606
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1. Di L, Kerns EH. Drug-Like Properties: concepts, Structure Design, and Methods. London (UK): Elevier; 2016.
2. Property-Based Design: Optimization of Drug Absorption and Pharmacokinetics
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4. Why 90% of clinical drug development fails and how to improve it?
5. Pharmacokinetics and Metabolism in Drug Design
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