Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model-Reference-Cited by-同舟云学术

Evaluation of Tissue Binding in Three Tissues across Five Species and Prediction of Volume of Distribution from Plasma Protein and Tissue Binding with an Existing Model

Published:2021-02-02 Issue:4 Volume:49 Page:330-336
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Hsu Frederick,Chen Yi-Chen,Broccatelli Fabio^ORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

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4. Why decreasing lipophilicity alone is often not a reliable strategy for extending IV half-life;Broccatelli;ACS Med Chem Lett,2018

5. Strategies to optimize drug half-life in lead candidate identification;Broccatelli;Expert Opin Drug Discov,2019

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