Unbound Fractions of PFAS in Human and Rodent Tissues: Rat Liver a Suitable Proxy for Evaluating Emerging PFAS?

Author:

Ryu Sangwoo12,Burchett Woodrow2,Zhang Sam2,Jia Xuelian34,Modaresi Seyed Mohamad Sadegh1,Agudelo Areiza Juliana1,Rodrigues David2,Zhu Hao34ORCID,Sunderland Elsie M.5ORCID,Fischer Fabian Christoph15ORCID,Slitt Angela L.1ORCID

Affiliation:

1. Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, Rhode Island 02881, United States

2. Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research & Development, Pfizer Incorporated, Groton, Connecticut 06340, United States

3. Department of Chemistry and Biochemistry, Rowan University, Glassboro, New Jersey 08028, United States

4. Center for Biomedical Informatics and Genomics, Tulane University, New Orleans, Louisiana 70112, United States

5. Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, United States

Funder

National Institute of Environmental Health Sciences

National Institute of Child Health and Human Development

National Institute of General Medical Sciences

National Science Foundation

Publisher

American Chemical Society (ACS)

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