Newly Identified Tree ShrewCytochrome P4502A13 is Expressed in Liver and Lung and Encodes a Functional Drug-Metabolizing Enzyme Similar to DogCytochrome P4502A13 and PigCytochrome P4502A19
Author:
Publisher
American Society for Pharmacology & Experimental Therapeutics (ASPET)
Subject
Pharmaceutical Science,Pharmacology
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1. Molecular and functional characterization of flavin-containing monooxygenases (FMO1–6) in tree shrews;Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology;2024-03
2. Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity;Biochemical Pharmacology;2023-12
3. Tree shrew cytochrome P450 2E1 is a functional enzyme that metabolises chlorzoxazone and p -nitrophenol;Xenobiotica;2023-11-02
4. Newly identified cytochrome P450 3A genes of tree shrews and pigs are expressed and encode functional enzymes;Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology;2023-05
5. 2-Oxidation, 3-methyl hydroxylation, and 6-hydroxylation of skatole, a contributor to the odour of boar-tainted pork meat, mediated by porcine liver microsomal cytochromes P450 1A2, 2A19, 2E1, and 3A22;Xenobiotica;2023-01-02
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