Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity-Reference-Cited by-同舟云学术

Identification of cytochrome P450 2C18 and 2C76 in tree shrews: P450 2C18 effectively oxidizes typical human P450 2C9/2C19 chiral substrates warfarin and omeprazole with less stereoselectivity

Published:2023-12 Issue: Volume: Page:115990
ISSN:0006-2952
Container-title:Biochemical Pharmacology
language:en
Short-container-title:Biochemical Pharmacology

Author:

Uno Yasuhiro,Minami Yuhki,Tsukiyama-Kohara Kyoko,Murayama Norie,Yamazaki Hiroshi^ORCID

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Pharmacology,Biochemistry

Reference35 articles.

1. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants;Nelson;Pharmacogenetics,2004

2. Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians;Shimada;J Pharmacol Exp Ther,1994

3. The human intestinal cytochrome P450 “pie”;Paine;Drug Metab Dispos,2006

4. Clinical relevance of genetic polymorphisms in the human CYP2C subfamily;Goldstein;Br J Clin Pharmacol,2001

5. Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation;Zanger;Pharmacol Ther,2013

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Molecular and functional characterization of flavin-containing monooxygenases (FMO1–6) in tree shrews;Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology;2024-03