Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity-Reference-Cited by-同舟云学术

Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity

Published:2022-11-22 Issue:2 Volume:51 Page:165-173
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Hishinuma Eiji,Narita Yoko,Rico Evelyn Marie Gutiérrez,Ueda Akiko,Obuchi Kai,Tanaka Yoshikazu,Saito Sakae,Tadaka Shu,Kinoshita Kengo,Maekawa Masamitsu,Mano Nariyasu,Nakayoshi Tomoki,Oda Akifumi,Hirasawa Noriyasu,Hiratsuka Masahiro^ORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference37 articles.

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2. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for Dihydropyrimidine Dehydrogenase Genotype and Fluoropyrimidine Dosing: 2017 update;Amstutz;Clin Pharmacol Ther,2018

3. Dihydropyrimidinuria: a new inborn error of pyrimidine metabolism

4. Dihydropyrimidinase Deficiency: Structural Organization, Chromosomal Localization, and Mutation Analysis of the Human Dihydropyrimidinase Gene

5. Possible prediction of adverse reactions to pyrimidine chemotherapy from urinary pyrimidine levels and a case of asymptomatic adult dihydropyrimidinuria;Hayashi;Clin Cancer Res,1996

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1. Common dihydropyrimidinase (DPYS) genetic variations do not predict fluoropyrimidine-related chemotherapy toxicity in a Canadian cohort;Pharmacogenetics and Genomics;2024-01-15

2. The burden of rare variants in DPYS gene is a novel predictor of the risk of developing severe fluoropyrimidine-related toxicity;Human Genomics;2023-11-09

3. jMorp: Japanese Multi-Omics Reference Panel update report 2023;Nucleic Acids Research;2023-11-01