Characterization of Ritonavir-Mediated Inactivation of Cytochrome P450 3A4-Reference-Cited by-同舟云学术

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Characterization of Ritonavir-Mediated Inactivation of Cytochrome P450 3A4

Published:2014-10-01 Issue:6 Volume:86 Page:665-674
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Rock Brooke M.,Hengel Shawna M.,Rock Dan A.,Wienkers Larry C.,Kunze Kent L.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference37 articles.

1. Time-Dependent Inactivation of P450 3A4 by Raloxifene: Identification of Cys239 as the Site of Apoprotein Alkylation1

2. Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver

3. Particular ability of cytochromes P450 3A to form inhibitory P450-iron-metabolite complexes upon metabolic oxidation of aminodrugs

4. Mechanism-Based Inactivation of Cytochromes P450 2E1 and 2E1 T303A by tert-Butyl Acetylenes: Characterization of Reactive Intermediate Adducts to the Heme and Apoprotein

5. The cytochrome P-450 metabolite complex derived from troleandomycin: Properties in vitro and stability in vivo

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