Mechanism-Based Inactivation of Cytochromes P450 2E1 and 2E1 T303A by tert-Butyl Acetylenes: Characterization of Reactive Intermediate Adducts to the Heme and Apoprotein-Reference-Cited by-同舟云学术

Mechanism-Based Inactivation of Cytochromes P450 2E1 and 2E1 T303A by tert-Butyl Acetylenes: Characterization of Reactive Intermediate Adducts to the Heme and Apoprotein

Published:2002-11-14 Issue:12 Volume:15 Page:1561-1571
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Blobaum Anna L.¹,Kent Ute M.¹,Alworth William L.¹,Hollenberg Paul F.¹

Affiliation:

1. Department of Pharmacology, The University of Michigan, Ann Arbor, Michigan 48109, and Department of Chemistry, Tulane University, New Orleans, Louisiana 70118

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx020052x

Reference38 articles.

1. P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

2. High-resolution crystal structure of cytochrome P450cam

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