Novel Molecular Determinants in the Pore Region of Sodium Channels Regulate Local Anesthetic Binding-Reference-Cited by-同舟云学术

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Novel Molecular Determinants in the Pore Region of Sodium Channels Regulate Local Anesthetic Binding

Published:2009-07-20 Issue:4 Volume:76 Page:861-871
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Yamagishi Toshio,Xiong Wei,Kondratiev Andre,Vélez Patricio,Méndez-Fitzwilliam Ailsa,Balser Jeffrey R.,Marbán Eduardo,Tomaselli Gordon F.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference59 articles.

1. Electrostatic Contributions of Aromatic Residues in the Local Anesthetic Receptor of Voltage-Gated Sodium Channels

2. External pore residue mediates slow inactivation in mu 1 rat skeletal muscle sodium channels.

3. Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels.

4. External site for local anesthetic block of cardiac Na+ channels*1

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1. Structure of Sodium and Calcium Channels with Ligands;Journal of Evolutionary Biochemistry and Physiology;2021-03

2. Opposing Effects on Na V 1.2 Function Underlie Differences Between SCN2A Variants Observed in Individuals With Autism Spectrum Disorder or Infantile Seizures;Biological Psychiatry;2017-08

3. Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants;Journal of General Physiology;2017-03-03

4. Structural Models of Ligand-Bound Sodium Channels;Voltage-gated Sodium Channels: Structure, Function and Channelopathies;2017

5. Effect of dibucaine hydrochloride on raft-like lipid domains in model membrane systems;MedChemComm;2015

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