Characterization of SB-705498, a Potent and Selective Vanilloid Receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor-Reference-Cited by-同舟云学术

Characterization of SB-705498, a Potent and Selective Vanilloid Receptor-1 (VR1/TRPV1) Antagonist That Inhibits the Capsaicin-, Acid-, and Heat-Mediated Activation of the Receptor

Published:2007-03-28 Issue:3 Volume:321 Page:1183-1192
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Gunthorpe Martin J.,Hannan Sara Luis,Smart Darren,Jerman Jeffrey C.,Arpino Sandra,Smith Graham D.,Brough Stephen,Wright Jim,Egerton Julie,Lappin Sarah C.,Holland Vicky A.,Winborn Kim,Thompson Mervyn,Rami Harshad K.,Randall Andrew,Davis John B.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

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1. Anandamide acts as a vasodilator of dural blood vessels in vivo by activating TRPV1 receptors

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3. Clues to understanding cold sensation: Thermodynamics and electrophysiological analysis of the cold receptor TRPM8

4. The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway

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