TRPV1 analgesics disturb core body temperature via a biased allosteric mechanism involving conformations distinct from that for nociception-Reference-Cited by-同舟云学术

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TRPV1 analgesics disturb core body temperature via a biased allosteric mechanism involving conformations distinct from that for nociception

Published:2024-06 Issue:11 Volume:112 Page:1815-1831.e4
ISSN:0896-6273
Container-title:Neuron
language:en
Short-container-title:Neuron

Author:

Huang Yi-Zhe,Ma Jing-Xian,Bian Yu-Jing,Bai Qin-Ru,Gao Yu-Hao,Di Shu-Ke,Lei Yun-Tao,Yang Hui,Yang Xiao-Na,Shao Chang-Yan,Wang Wen-Hui,Cao Peng,Li Chang-Zhu,Zhu Michael X.,Sun Meng-Yang,Yu Ye

Publisher

Elsevier BV

Reference64 articles.

1. Advances in TRP channel drug discovery: from target validation to clinical studies;Koivisto;Nat. Rev. Drug Discov.,2022

2. The capsaicin receptor: a heat-activated ion channel in the pain pathway;Caterina;Nature,1997

3. The cloned capsaicin receptor integrates multiple pain-producing stimuli;Tominaga;Neuron,1998

4. TRP channels and pain;Julius;Annu. Rev. Cell Dev. Biol.,2013

5. Impaired nociception and pain sensation in mice lacking the capsaicin receptor;Caterina;Science,2000

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of first-in-class highly selective TRPV1 antagonists with dual analgesic and hypoglycemic effects;Bioorganic & Medicinal Chemistry;2024-06

2. Turning down the body heat: A novel mechanism for TRPV1 antagonist-induced hyperthermia;Neuron;2024-06

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