Characterizing the Pharmacokinetics and Biodistribution of Therapeutic Proteins: An Industry White Paper-Reference-Cited by-同舟云学术

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Characterizing the Pharmacokinetics and Biodistribution of Therapeutic Proteins: An Industry White Paper

Published:2022-02-11 Issue:6 Volume:50 Page:858-866
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Ball Kathryn,Bruin Gerard,Escandón Enrique,Funk Christoph,Pereira Joao N.S.,Yang Tong-Yuan,Yu Hongbin

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference85 articles.

1. Utility of a human FcRn transgenic mouse model in drug discovery for early assessment and prediction of human pharmacokinetics of monoclonal antibodies

2. Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics;Avery;MAbs,2018

3. Linear pharmacokinetic parameters for monoclonal antibodies are similar within a species and across different pharmacological targets: A comparison between human, cynomolgus monkey and hFcRn Tg32 transgenic mouse using a population-modeling approach;Betts;MAbs,2018

4. A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Mediated Tumor Cell Killing by P-Cadherin LP DART®;Betts;AAPS J,2019

5. Absorption, Distribution, Metabolism, and Excretion (ADME) of Therapeutic Proteins: Current Industry Practices and Future Perspectives;Bolleddula;Drug Metab Dispos,2022

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