A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor-Reference-Cited by-同舟云学术

A Genomic DNA Reporter Screen Identifies Squalene Synthase Inhibitors That Act Cooperatively with Statins to Upregulate the Low-Density Lipoprotein Receptor

Published:2017-03-30 Issue:3 Volume:361 Page:417-428
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Kerr Alastair G.,Tam Lawrence C. S.,Hale Ashley B.,Cioroch Milena,Douglas Gillian,Agkatsev Sarina,Hibbitt Olivia,Mason Joseph,Holt-Martyn James,Bataille Carole J. R.,Wynne Graham M.,Channon Keith M.,Russell Angela J.,Wade-Martins Richard

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference37 articles.

1. Bisphosphonates used for the treatment of bone disorders inhibit squalene synthase and cholesterol biosynthesis;Amin;J Lipid Res,1992

2. Statin Safety: An Overview and Assessment of the Data—2005

3. Intolerance to Statins: Mechanisms and Management

4. Camus M, Chapman MJ, Forgez P, and Laplaud PM (1983) Distribution and characterization of the serum lipoproteins and apoproteins in the mouse, Mus musculus. J Lipid Res 24:1210–1228.

5. Squalene synthase inhibition: A novel target for the management of dyslipidemia

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mutant p53, the Mevalonate Pathway and the Tumor Microenvironment Regulate Tumor Response to Statin Therapy;Cancers;2022-07-19

2. From 2-Triethylammonium Ethyl Ether of 4-Stilbenol (MG624) to Selective Small-Molecule Antagonists of Human α9α10 Nicotinic Receptor by Modifications at the Ammonium Ethyl Residue;Journal of Medicinal Chemistry;2022-07-14

3. Cholesterol metabolism in prostate cancer;Prostate Cancer Metabolism;2021

4. A factorial Mendelian randomization study to systematically prioritize genetic targets for the treatment of cardiovascular disease;2020-02-20

5. Bovine Lactoferrin Inhibits Dengue Virus Infectivity by Interacting with Heparan Sulfate, Low-Density Lipoprotein Receptor, and DC-SIGN;International Journal of Molecular Sciences;2017-09-12