Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity-Reference-Cited by-同舟云学术

Stereoselective Oxidation Kinetics of Deoxycholate in Recombinant and Microsomal CYP3A Enzymes: Deoxycholate 19-Hydroxylation Is an In Vitro Marker of CYP3A7 Activity

Published:2019-03-27 Issue:6 Volume:47 Page:574-581
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Chen Yu-Jie,Zhang Jian,Zhu Ping-Ping,Tan Xian-Wen,Lin Qiu-Hong,Wang Wen-Xia,Yin Shan-Shan,Gao Ling-Zhi,Su Ming-Ming,Liu Chang-Xiao,Xu Liang,Jia Wei,Sevrioukova Irina F.,Lan Ke^ORCID

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference41 articles.

1. CYP3A7*1C polymorphism, serum dehydroepiandrosterone sulfate level, and bone mineral density in postmenopausal women;Bácsi;Calcif Tissue Int,2007

2. Intestinal transport and metabolism of bile acids

3. de Montellano PRO (2009) Cytochrome P-450: Structure, Mechanism, and Biochemistry, Springer, Berlin.

4. Protein abundance of clinically relevant drug-metabolizing enzymes in the human liver and intestine: a comparative analysis in paired tissue specimens;Drozdzik;Clin Pharmacol Ther,2018

5. Two-dimensional NMR study on the structures of micelles of sodium taurocholate;Funasaki;J Phys Chem B,2004

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