An in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 Enzymes-Reference-Cited by-同舟云学术

An in Vitro Evaluation of the Victim and Perpetrator Potential of the Anticancer Agent Laromustine (VNP40101M), Based on Reaction Phenotyping and Inhibition and Induction of Cytochrome P450 Enzymes

Published:2009-06-11 Issue:9 Volume:37 Page:1922-1930
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Nassar Alaa-Eldin F.,King Ivan,Paris Brandy L.,Haupt Lois,Ndikum-Moffor Florence,Campbell Rebecca,Usuki Etsuko,Skibbe Jennifer,Brobst Dan,Ogilvie Brian W.,Parkinson Andrew

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference19 articles.

1. Purification of two isozymes of rat liver microsomal cytochrome P450 with testosterone 7α-hydroxylase activity

2. The Antineoplastic Efficacy of the Prodrug CloretazineTM Is Produced by the Synergistic Interaction of Carbamoylating and Alkylating Products of its Activation

3. THE CONDUCT OF IN VITRO AND IN VIVO DRUG-DRUG INTERACTION STUDIES: A PHARMACEUTICAL RESEARCH AND MANUFACTURERS OF AMERICA (PhRMA) PERSPECTIVE

4. A Phase I and Pharmacokinetic Study of VNP40101M, a Novel Sulfonylhydrazine Alkylating Agent, in Patients with Refractory Leukemia

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