Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans-Reference-Cited by-同舟云学术

Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans

Published:2007-07-26 Issue:10 Volume:35 Page:1916-1925
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Qian Mingxin,Bai Stephen A.,Brogdon Bernice,Wu Jing-Tao,Liu Rui-Qin,Covington Maryanne B.,Vaddi Kris,Newton Robert C.,Fossler Michael J.,Garner C. Edwin,Deng Yuzhong,Maduskuie Thomas,Trzaskos James,Duan James J.-W.,Decicco Carl P.,Christ David D.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference34 articles.

1. Epidemiology of adult rheumatoid arthritis

2. (E)-2(R)-[1(S)-(Hydroxycarbamoyl)-4-phenyl-3-butenyl]-2′-isobutyl-2′-(methanesulfonyl)-4-methylvalerohydrazide (Ro 32-7315), a Selective and Orally Active Inhibitor of Tumor Necrosis Factor-α Convertase

3. Binding of Diltiazem to Albumin, α1-Acid Glycoprotein and to Serum in Man

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