Isoform-Selective Inhibition of Phosphoinositide 3-Kinase: Identification of a New Region of Nonconserved Amino Acids Critical for p110α Inhibition-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Isoform-Selective Inhibition of Phosphoinositide 3-Kinase: Identification of a New Region of Nonconserved Amino Acids Critical for p110α Inhibition

Published:2011-07-21 Issue:4 Volume:80 Page:657-664
ISSN:0026-895X
Container-title:Molecular Pharmacology
language:en
Short-container-title:Mol Pharmacol

Author:

Zheng Zhaohua,Amran Syazwani I.,Thompson Philip E.,Jennings Ian G.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference24 articles.

1. The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors

2. New phosphatidylinositol 3-kinase inhibitors for cancer;Bowles;Expert Opin Investig Drugs,2011

3. Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis;Camps;Nat Med,2005

4. Dissecting isoform selectivity of PI3K inhibitors: the role of non-conserved residues in the catalytic pocket

5. Phosphoinositide-3-kinases (PI3Ks): Combined Comparative Modeling and 3D-QSAR To Rationalize the Inhibition of p110α

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transition-Metal-Free Sulfoximidation of Sulfonylhydrazones for the Synthesis of N-Sulfanylidenehydrazonamides;Organic Letters;2024-07-26

2. Allosteric PI3Kα Inhibition Overcomes On-target Resistance to Orthosteric Inhibitors Mediated by Secondary PIK3CA Mutations;Cancer Discovery;2024-01-03

3. Quantum biochemistry description of PI3Kα enzyme bound to selective inhibitors;Journal of Biomolecular Structure and Dynamics;2023-08-26

4. Identification of Potential p38γ Inhibitors via In Silico Screening, In Vitro Bioassay and Molecular Dynamics Simulation Studies;International Journal of Molecular Sciences;2023-04-17

5. Development of PI3Kα inhibitors for tumor therapy;Journal of Biomolecular Structure and Dynamics;2022-10-11

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3