Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder-Reference-Cited by-同舟云学术

Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder

Published:2012-05-08 Issue:2 Volume:342 Page:429-440
ISSN:0022-3565
Container-title:Journal of Pharmacology and Experimental Therapeutics
language:en
Short-container-title:J Pharmacol Exp Ther

Author:

Bonaventure Pascal,Dugovic Christine,Kramer Michelle,De Boer Peter,Singh Jaskaran,Wilson Sue,Bertelsen Kirk,Di Jianing,Shelton Jonathan,Aluisio Leah,Dvorak Lisa,Fraser Ian,Lord Brian,Nepomuceno Diane,Ahnaou Abdellah,Drinkenburg Wilhelmus,Chai Wenying,Dvorak Curt,Sands Steve,Carruthers Nicholas,Lovenberg Timothy W.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmacology,Molecular Medicine

Reference36 articles.

1. Synthesis and biological evaluation of potential 5-HT7 receptor PET radiotracers

2. Selective Blockade of 5-Hydroxytryptamine (5-HT)7Receptors Enhances 5-HT Transmission, Antidepressant-Like Behavior, and Rapid Eye Movement Sleep Suppression Induced by Citalopram in Rodents

3. Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

4. The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor

5. Characterization of SB-269970-A, a selective 5-HT7receptor antagonist

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