Characterization of SB-269970-A, a selective 5-HT7receptor antagonist

Author:

Hagan Jim J,Price Gary W,Jeffrey Phillip,Deeks Nigel J,Stean Tania,Piper David,Smith Martin I,Upton Neil,Medhurst Andrew D,Middlemiss Derek N,Riley Graham J,Lovell Peter J,Bromidge Steven M,Thomas David R

Publisher

Wiley

Subject

Pharmacology

Reference40 articles.

1. Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase;BARD;J. Biol. Chem.,1993

2. High specific activity [3H]-5-CT binding: correlation of guinea-pig cortex with human cloned 5-HT7 receptors;BOYLAND;Br. J. Pharmacol.,1996

3. Autoradiographic localisation of 5-HT7 and its mRNA in rat CNS by radioligand binding and in situ hybridization histochemistry;BRANCHEK;Br. J. Pharmacol.,1994

4. Pharmacological studies with SK&F 93944 (temelastine), a novel histamine H1-receptor antagonist with negligible ability to penetrate the central nervous system;BROWN;Br. J. Pharmacol.,1986

5. Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction;CHENG;Biochem. Pharmacol.,1973

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