ICI 56,780 Optimization: Structure–Activity Relationship Studies of 7-(2-Phenoxyethoxy)-4(1H)-quinolones with Antimalarial Activity

Author:

Maignan Jordany R.1,Lichorowic Cynthia L.12,Giarrusso James1,Blake Lynn D.3,Casandra Debora3,Mutka Tina S.3,LaCrue Alexis N.3,Burrows Jeremy N.4,Willis Paul A.4,Kyle Dennis E.3,Manetsch Roman125

Affiliation:

1. Department of Chemistry, University of South Florida, CHE 205, 4202 E. Fowler Avenue, Tampa, Florida 33620, United States

2. Department of Chemistry and Chemical Biology, Northeastern University, 102 Hurtig Hall, 360 Huntington Avenue, Boston, Massachusetts 02115, United States

3. Department of Global Health, College of Public Health, University of South Florida, 3720 Spectrum Boulevard, Suite 304, Tampa, Florida 33612, United States

4. Medicines for Malaria Venture, 20, Route de Pré-Bois, P.O. Box 1826, 1215 Geneva 15, Switzerland

5. Department of Pharmaceutical Sciences, Northeastern University, 102 Hurtig Hall, 360 Huntington Avenue, Boston, Massachusetts 02115, United States

Funder

Medicines for Malaria Venture

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference37 articles.

1. Antimalarial drug resistance: new treatments options for Plasmodium

2. World Health Organization. Malaria Fact Sheethttp://www.who.int/mediacentre/factsheets/fs094/en/(accessed Jun 22, 2015) .

3. Centers for Disease Control and Prevention. Biology.http://www.cdc.gov/malaria/about/biology/(accessed Jun 22, 2015) .

4. Structure and Life Cycle

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