Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis-Reference-Cited by-同舟云学术

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis

Published:2017-02-03 Issue:4 Volume:60 Page:1379-1399
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tantry Subramanyam J.¹,Markad Shankar D.¹,Shinde Vikas¹,Bhat Jyothi¹,Balakrishnan Gayathri¹,Gupta Amit K.¹^ORCID,Ambady Anisha¹,Raichurkar Anandkumar¹,Kedari Chaitanyakumar¹,Sharma Sreevalli¹,Mudugal Naina V.¹,Narayan Ashwini¹,Naveen Kumar C. N.¹,Nanduri Robert¹,Bharath Sowmya¹,Reddy Jitendar¹,Panduga Vijender¹,Prabhakar K. R.¹,Kandaswamy Karthikeyan¹,Saralaya Ramanatha¹,Kaur Parvinder¹,Dinesh Neela¹,Guptha Supreeth¹,Rich Kirsty²,Murray David²,Plant Helen²,Preston Marian²,Ashton Helen²,Plant Darren²,Walsh Jarrod²,Alcock Peter²,Naylor Kathryn²,Collier Matthew²,Whiteaker James³,McLaughlin Robert E.³,Mallya Meenakshi¹,Panda Manoranjan¹,Rudrapatna Suresh¹,Ramachandran Vasanthi¹,Shandil Radha¹,Sambandamurthy Vasan K.¹,Mdluli Khisi⁴,Cooper Christopher B.⁴,Rubin Harvey⁵,Yano Takahiro⁵,Iyer Pravin¹,Narayanan Shridhar¹,Kavanagh Stefan²,Mukherjee Kakoli¹,Balasubramanian V.¹,Hosagrahara Vinayak P.¹,Solapure Suresh¹,Ravishankar Sudha¹^ORCID,Hameed P Shahul¹

Affiliation:

1. Innovative Medicines, AstraZeneca India Pvt. Ltd., Bellary Road, Hebbal, Bangalore 560024, India

2. AstraZeneca, Alderley Park, Mereside, Macclesfield, Cheshire U.K. SK10 4TG

3. Infection Innovative Medicines, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

4. Global Alliance for TB Drug Development, 40 Wall Street, 24th Floor, New York, New York 10005, United States

5. University of Pennsylvania, 111 Clinical Research Building, 415 Curie Boulevard, Philadelphia Pennsylvania 19104, United States

Funder

Global Alliance for TB Drug Development

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01358

Reference51 articles.

1. Global Tuberculosis Report 2015,20thed.World Health Organization:Geneva, 2015; http://apps.who.int/iris/bitstream/10665/191102/1/9789241565059_eng.pdf(accessed Oct 7, 2015).

2. The Population Dynamics and Control of Tuberculosis

3. Tuberculosis

4. Multidrug-resistant and extensively drug-resistant tuberculosis: a threat to global control of tuberculosis

5. Virtually incurable TB warns of impending disaster

Cited by 103 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs;2024-08-24

2. The Liebeskind–Srogl Cross-Coupling Reaction as a Crucial Step in the Synthesis of New Squaramide-Based Antituberculosis Agents;ACS Omega;2024-07-29

3. The Structure–Antiproliferative Activity Relationship of Pyridine Derivatives;International Journal of Molecular Sciences;2024-07-11

4. 3-[(Benzo-1,3-dioxol-5-yl)amino]-4-methoxycyclobut-3-ene-1,2-dione: polymorphism and twinning of a precursor to an antimycobacterial squaramide;Acta Crystallographica Section C Structural Chemistry;2024-07-05

5. Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587;Nature;2024-07-03