Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa-Reference-Cited by-同舟云学术

Heterocyclyl Tetracyclines. 1. 7-Trifluoromethyl-8-Pyrrolidinyltetracyclines: Potent, Broad Spectrum Antibacterial Agents with Enhanced Activity against Pseudomonas aeruginosa

Published:2017-03-15 Issue:6 Volume:60 Page:2498-2512
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Deng Yonghong¹^ORCID,Sun Cuixiang¹,Hunt Diana K.¹,Fyfe Corey¹,Chen Chi-Li¹,Grossman Trudy H.¹,Sutcliffe Joyce A.¹,Xiao Xiao-Yi¹

Affiliation:

1. Discovery Chemistry, ‡Microbiology, Tetraphase Pharmaceuticals, 480 Arsenal Way, Watertown, Massachusetts 02472, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01903

Reference36 articles.

1. AUREOMYCIN: A PRODUCT OF THE CONTINUING SEARCH FOR NEW ANTIBIOTICS

2. bDuggar, B. M.Aureomycin and Preparation of Same, US2482055, Sept 13, 1949.

3. Discovery of Drugs from Microbiological Sources

4. The growing burden of antimicrobial resistance

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