Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8-Reference-Cited by-同舟云学术

Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8

Published:2016-04-29 Issue:10 Volume:59 Page:4753-4768
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gardinier Kevin M.¹,Gernert Douglas L.¹,Porter Warren J.¹,Reel Jon K.¹,Ornstein Paul L.¹,Spinazze Patrick¹,Stevens F. Craig¹,Hahn Patric¹,Hollinshead Sean P.¹,Mayhugh Daniel¹,Schkeryantz Jeff¹,Khilevich Albert¹,De Frutos Oscar¹,Gleason Scott D.¹,Kato Akihiko S.¹,Luffer-Atlas Debra¹,Desai Prashant V.¹,Swanson Steven¹,Burris Kevin D.¹,Ding Chunjin¹,Heinz Beverly A.¹,Need Anne B.¹,Barth Vanessa N.¹,Stephenson Gregory A.¹,Diseroad Benjamin A.¹,Woods Tim A.¹,Yu Hong¹,Bredt David¹,Witkin Jeffrey M.¹

Affiliation:

1. Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285 United States

Funder

Eli Lilly and Company

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00125

Reference35 articles.

1. The global burden and stigma of epilepsy