Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84-Reference-Cited by-同舟云学术

Diindolylmethane Derivatives: Potent Agonists of the Immunostimulatory Orphan G Protein-Coupled Receptor GPR84

Published:2017-05-01 Issue:9 Volume:60 Page:3636-3655
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pillaiyar Thanigaimalai¹,Köse Meryem¹,Sylvester Katharina¹,Weighardt Heike²,Thimm Dominik¹,Borges Gleice¹,Förster Irmgard²,von Kügelgen Ivar³,Müller Christa E.¹^ORCID

Affiliation:

1. PharmaCenter Bonn, Pharmaceutical Institute, Pharmaceutical Chemistry I, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany

2. Life and Medical Sciences (LIMES) Institute, Immunology and Environment, University of Bonn, Carl-Troll-Straße 31, 53115 Bonn, Germany

3. Department of Pharmacology and Toxicology, University of Bonn, 53105 Bonn, Germany

Funder

Bayer

Deutsche Forschungsgemeinschaft

Ministério da Educação

Alexander von Humboldt-Stiftung

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01593

Reference98 articles.

1. Trends in the exploitation of novel drug targets

2. Orphan GPCR research

3. The Orphan G Protein-coupled Receptor GPR40 Is Activated by Medium and Long Chain Fatty Acids

4. The Orphan G Protein-coupled Receptors GPR41 and GPR43 Are Activated by Propionate and Other Short Chain Carboxylic Acids

5. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120

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