Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin-Reference-Cited by-同舟云学术

Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin

Published:2016-11-14 Issue:22 Volume:59 Page:10329-10334
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhou Pengfei¹,Liu Yan²,Zhou Lu¹,Zhu Kongkai²,Feng Kechang¹,Zhang Hao²,Liang Yuru¹,Jiang Hualiang²,Luo Cheng²,Liu Mingming¹,Wang Yang¹

Affiliation:

1. School of Pharmacy, Fudan University, Shanghai 201203, China

2. Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

State Key Laboratory of Toxicology and Medical Countermeasures, Academy of Military Medical Science

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01268

Reference22 articles.

1. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle

2. An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site

3. Tubulin-interactive stilbene derivatives as anticancer agents

4. Recent developments in tubulin polymerization inhibitors: An overview

5. Design, Synthesis, and Biological Evaluation of Novel Pyridine-Bridged Analogues of Combretastatin-A4 as Anticancer Agents

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