Potent Antitumor Activities and Structure Basis of the Chiral β-Lactam Bridged Analogue of Combretastatin A-4 Binding to Tubulin
Author:
Affiliation:
1. School of Pharmacy, Fudan University, Shanghai 201203, China
2. Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China
Funder
Ministry of Science and Technology of the People's Republic of China
National Natural Science Foundation of China
State Key Laboratory of Toxicology and Medical Countermeasures, Academy of Military Medical Science
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01268
Reference22 articles.
1. Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle
2. An Overview of Tubulin Inhibitors That Interact with the Colchicine Binding Site
3. Tubulin-interactive stilbene derivatives as anticancer agents
4. Recent developments in tubulin polymerization inhibitors: An overview
5. Design, Synthesis, and Biological Evaluation of Novel Pyridine-Bridged Analogues of Combretastatin-A4 as Anticancer Agents
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