Rational Design, Synthesis, and Biological Evaluation of 7-Azaindole Derivatives as Potent Focused Multi-Targeted Kinase Inhibitors
Author:
Affiliation:
1. OriBase Pharma, Cap Gamma, Parc Euromédecine, 1682 rue de la Valsière, CS 17383, Montpellier 34189 CEDEX 4, France
Funder
OriBase Pharma
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b00087
Reference23 articles.
1. Targeting cancer with small molecule kinase inhibitors
2. Recently targeted kinases and their inhibitors—the path to clinical trials
3. Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
4. Selection and adaptation during metastatic cancer progression
5. Targeting Multiple Kinase Pathways: A Change In Paradigm: Fig. 1.
Cited by 45 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. I2/CAN as an efficient reagent for the direct oxidation of tertiary Csp3-H to Csp3-OH: Synthesis of bis(N-methyl-7-azaindol-3-yl) (phenyl) methanol from 3,3′-(phenyl methylene)-bis(N-methyl-7-azaindole);Tetrahedron Letters;2024-09
2. Synthesis, enzyme inhibition assay, and molecular modeling study of novel pyrazolines linked to 4-methylsulfonylphenyl scaffold: antitumor activity and cell cycle analysis;RSC Advances;2024
3. I2/Can as an Efficient Reagent for the Direct Oxidation of Tertiary Csp3-H to Csp3-Oh: Synthesis of Bis(N-Methyl-7-Azaindol-3-Yl) (Phenyl) Methanol from 3,3'-(Phenyl Methylene)-Bis(N-Methyl-7-Azaindole);2024
4. An insight into the structure–activity relationship studies of anticancer medicinal attributes of 7-azaindole derivatives: a review;Future Medicinal Chemistry;2023-12
5. Medicinal Chemistry Perspectives on Recent Advances in Src Kinase Inhibitors as a Potential Target for the Development of Anticancer Agents: Biological Profile, Selectivity, Structure‐Activity Relationship;Chemistry & Biodiversity;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3