Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes-Reference-Cited by-同舟云学术

Discovery of LX2761, a Sodium-Dependent Glucose Cotransporter 1 (SGLT1) Inhibitor Restricted to the Intestinal Lumen, for the Treatment of Diabetes

Published:2017-01-17 Issue:2 Volume:60 Page:710-721
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Goodwin Nicole C.¹^ORCID,Ding Zhi-Ming,Harrison Bryce A.¹,Strobel Eric D.¹,Harris Angela L.,Smith Melinda,Thompson Andrea Y.,Xiong Wendy,Mseeh Faika,Bruce Debra J.,Diaz Damaris,Gopinathan Suma,Li Ling,O’Neill Emily,Thiel Mary,Wilson Alan G. E.,Carson Kenneth G.¹,Powell David R.,Rawlins David B.¹

Affiliation:

1. Department of Medicinal Chemistry, Lexicon Pharmaceuticals, 110 Allen Road, Basking Ridge, New Jersey 07920, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.6b01541

Reference65 articles.

1. Diabetes Fact Sheet.www.who.int/mediacentre/factsheets/fs312/en(accessed March 6, 2016) .

2. Microvascular and Macrovascular Complications of Diabetes

3. Mortality and causes of death in the WHO multinational study of vascular disease in diabetes