Into Deep Water: Optimizing BCL6 Inhibitors by Growing into a Solvated Pocket
Author:
Funder
Pioneer Fund
Cancer Research UK
Sixth Element Capital
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00946
Reference21 articles.
1. Diffuse large B‐cell lymphoma: 2019 update on diagnosis, risk stratification, and treatment
2. Structure of a BCOR Corepressor Peptide in Complex with the BCL6 BTB Domain Dimer
3. Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells
4. The Transcriptional Regulation of Germinal Center Formation
5. Roles of BCL6 in normal and transformed germinal center B cells
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