Selection of QPX7831, an Orally Bioavailable Prodrug of Boronic Acid β-Lactamase Inhibitor QPX7728-Reference-Cited by-同舟云学术

Selection of QPX7831, an Orally Bioavailable Prodrug of Boronic Acid β-Lactamase Inhibitor QPX7728

Published:2021-11-24 Issue:23 Volume:64 Page:17523-17529
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Reddy K. Raja¹,Parkinson Jonathan¹^ORCID,Sabet Mojgan¹,Tarazi Ziad¹,Boyer Serge H.¹,Lomovskaya Olga¹,Griffith David C.¹,Hecker Scott J.¹^ORCID,Dudley Michael N.¹

Affiliation:

1. Qpex Biopharma, Inc., 6275 Nancy Ridge Drive, Suite 100, San Diego, California 92121, United States

Funder

Biomedical Advanced Research and Development Authority (BARDA)

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01722

Reference16 articles.

1. Global Fluoroquinolone Resistance Epidemiology and Implictions for Clinical Use

2. Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications

3. Epidemiology and Mechanisms of Resistance of Extensively Drug Resistant Gram-Negative Bacteria

4. New β-Lactam–β-Lactamase Inhibitor Combinations

5. Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases

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