Design and Structure–Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors-Reference-Cited by-同舟云学术

Design and Structure–Activity Relationships of Isothiocyanates as Potent and Selective N-Acylethanolamine-Hydrolyzing Acid Amidase Inhibitors

Published:2021-04-26 Issue:9 Volume:64 Page:5956-5972
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Malamas Michael S.¹^ORCID,Pavlopoulos Spiro²,Alapafuja Shakiru O.³,Farah Shrouq I.²,Zvonok Alexander²,Mohammad Khadijah A.²,West Jay²,Perry Nicholas Thomas²,Pelekoudas Dimitrios N.²,Rajarshi Girija²,Shields Christina²,Chandrashekhar Honrao²,Wood Jodi²,Makriyannis Alexandros⁴

Affiliation:

1. Northeastern University, Boston, Massachusetts 02115, United States

2. Center for Drug Discovery, Northeastern University, Boston, Massachusetts 02115, United States

3. MAK Scientific LLC, 151 South Bedford Street, Burlington, Massachusetts 01803, United States

4. Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00076

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4. The anti-hyperalgesic actions of the cannabinoid anandamide and the putative CB2 receptor agonist palmitoylethanolamide in visceral and somatic inflammatory pain

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