Selective P450<sub>BM3</sub> Hydroxylation of Cyclobutylamine and Bicyclo[1.1.1]pentylamine Derivatives: Underpinning Synthetic Chemistry for Drug Discovery-Reference-Cited by-同舟云学术

Selective P450_BM3 Hydroxylation of Cyclobutylamine and Bicyclo[1.1.1]pentylamine Derivatives: Underpinning Synthetic Chemistry for Drug Discovery

Author:

Harwood Lucy A.¹^ORCID,Xiong Ziyue²,Christensen Kirsten E.¹,Wang Ruiyao³,Wong Luet L.²⁴^ORCID,Robertson Jeremy¹²^ORCID

Affiliation:

1. Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K.

2. Oxford Suzhou Centre for Advanced Research, Ruo Shui Road, Suzhou Industrial Park, Suzhou, Jiangsu 215123, P. R. China

3. Wisdom Lake Academy of Pharmacy, Xi’an Jiaotong-Liverpool University, Suzhou Industrial Park, Suzhou, Jiangsu, 215123, P. R. China

4. Inorganic Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford OX1 3QR, U.K.

Funder

Novartis

AstraZeneca

Defence Science and Technology Laboratory

Diamond Light Source

Pfizer

GlaxoSmithKline

Syngenta International

Janssen Pharmaceuticals

Engineering and Physical Sciences Research Council

Vertex Pharmaceuticals

UCB

Takeda Pharmaceutical Company

Biotechnology and Biological Sciences Research Council

Evotec

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

Reference64 articles.

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