Synthesis and Characterization of Transition-State Analogue Inhibitors against Human DNA Methyltransferase 1
Author:
Affiliation:
1. The Ferrier Research Institute, Victoria University of Wellington, P.O. Box 33436, Petone 5046, New Zealand
2. Biochemistry Department, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, United States
Funder
Ministry of Business, Innovation and Employment
National Institute of General Medical Sciences
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01869
Reference46 articles.
1. Epigenetic control of gene expression: Potential implications for cancer treatment
2. Epigenetic Therapeutics: A New Weapon in the War Against Cancer
3. Targeting DNA Methylation with Small Molecules: What’s Next?
4. DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies
5. Discovery and development of DNA methyltransferase inhibitors using in silico approaches
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