Structure–Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands

Author:

Fronik Philipp1,Poetsch Isabella123,Kastner Alexander1,Mendrina Theresa2,Hager Sonja2,Hohenwallner Katharina4,Schueffl Hemma2ORCID,Herndler-Brandstetter Dietmar2,Koellensperger Gunda4ORCID,Rampler Evelyn4ORCID,Kopecka Joanna5,Riganti Chiara5ORCID,Berger Walter23ORCID,Keppler Bernhard K.13,Heffeter Petra23,Kowol Christian R.13ORCID

Affiliation:

1. Faculty of Chemistry, Institute of Inorganic Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria

2. Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria

3. Research Cluster “Translational Cancer Therapy Research”, 1090 Vienna, Austria

4. Faculty of Chemistry, Institute of Analytical Chemistry, University of Vienna, Waehringer Strasse 38, 1090 Vienna, Austria

5. Department of Oncology, University of Torino, via Santena 5/bis, 10126 Torino, Italy

Funder

??sterreichischen Akademie der Wissenschaften

Austrian Science Fund

Associazione Italiana per la Ricerca sul Cancro

European Cooperation in Science and Technology

Fellinger Cancer Research Foundation

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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