Cytotoxic Pt(<scp>ii</scp>) complexes containing alizarin: a selective carrier for DNA metalation-Reference-Cited by-同舟云学术

Cytotoxic Pt(ii) complexes containing alizarin: a selective carrier for DNA metalation

Published:2024 Issue: Volume: Page:
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Caligiuri Rossella¹,Massai Lara²,Geri Andrea²,Ricciardi Loredana³^ORCID,Godbert Nicolas¹⁴^ORCID,Facchetti Giorgio⁵^ORCID,Lupo Maria Giovanna⁶,Rossi Ilaria⁷,Coffetti Giulia⁵,Moraschi Martina⁵,Sicilia Emilia⁸^ORCID,Vigna Vincenzo⁸,Messori Luigi²^ORCID,Ferri Nicola⁶⁹^ORCID,Mazzone Gloria⁸^ORCID,Aiello Iolinda¹⁴³^ORCID,Rimoldi Isabella⁵^ORCID

Affiliation:

1. MAT-INLAB, LASCAMM CR-INSTM, Unità INSTM della Calabria, Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Ponte Pietro Bucci Cubo 14C, Arcavacata di Rende (CS), 87036, Italy

2. Department of Chemistry, University of Florence, Via della Lastruccia 3-13, 50019 Sesto Fiorentino, Italy

3. CNR-Nanotec, UoS di Cosenza, Dipartimento di Fisica, Università della Calabria, 87036 Rende (CS), Italy

4. LPM-Laboratorio Preparazione Materiali, STAR-Lab, Università della Calabria, Via Tito Flavio, 87036 Rende (CS), Italy

5. Department of Pharmaceutical Sciences, University of Milan, Via Venezian 21, 20133 Milano, Italy

6. Department of Medicine, University of Padova, Italy

7. Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Italy

8. Dipartimento di Chimica e Tecnologie Chimiche, Università della Calabria, Ponte Pietro Bucci Cubo 14C, Arcavacata di Rende (CS), 87036, Italy

9. Veneto Institute of Molecular Medicine, Padua, Italy

Abstract

A series of neutral Pt(ii) complexes, bearing alizarin, were synthesized and characterized. In vitro cytotoxicity against triple negative breast cancer cell lines and their interaction with potential biological targets, were evaluated.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D3DT03889K

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