Design, Synthesis, and Structure–Activity Relationship Studies of Bisamide Derivatives of Amphotericin B with Potent Efficacy and Low Toxicity-Reference-Cited by-同舟云学术

Design, Synthesis, and Structure–Activity Relationship Studies of Bisamide Derivatives of Amphotericin B with Potent Efficacy and Low Toxicity

Published:2022-07-04 Issue:13 Volume:65 Page:8897-8913
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Ma Huijun¹²,Qian Anran¹²,Zheng Yazhou³,Meng Xin¹,Wang Ting⁴,Zhang Yinyong¹,Sun Lulu¹,Zou Feng⁴,Zhao Bomei⁴,Zhang Shuhua⁴,Zhang Dan¹²^ORCID,Yang Yushe¹²^ORCID

Affiliation:

1. State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, P. R. China

2. University of Chinese Academy of Sciences, Beijing 100049, P. R. China

3. Department of Chemistry, College of Sciences, Shanghai University, Shanghai 200444, P. R. China

4. Department of Microbiology, Sichuan Primed Bio-Tech Group Co., Ltd., Chengdu, Sichuan Province 610041, P. R. China

Funder

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c02227

Reference46 articles.

1. Global and Multi-National Prevalence of Fungal Diseases—Estimate Precision

2. Antifungal Drug Development: Challenges, Unmet Clinical Needs, and New Approaches

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