Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal-Reference-Cited by-同舟云学术

Tuning sterol extraction kinetics yields a renal-sparing polyene antifungal

Published:2023-11-08 Issue:7989 Volume:623 Page:1079-1085
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Maji Arun,Soutar Corinne P.^ORCID,Zhang Jiabao,Lewandowska Agnieszka,Uno Brice E.,Yan Su,Shelke Yogesh,Murhade Ganesh,Nimerovsky Evgeny,Borcik Collin G.,Arango Andres S.,Lange Justin D.,Marin-Toledo Jonnathan P.,Lyu Yinghuan,Bailey Keith L.,Roady Patrick J.,Holler Jordan T.,Khandelwal Anuj,SantaMaria Anna M.^ORCID,Sanchez Hiram,Juvvadi Praveen R.^ORCID,Johns Gina,Hageman Michael J.,Krise Joanna,Gebremariam Teclegiorgis^ORCID,Youssef Eman G.,Bartizal Ken^ORCID,Marr Kieren A.,Steinbach William J.,Ibrahim Ashraf S.^ORCID,Patterson Thomas F.,Wiederhold Nathan P.^ORCID,Andes David R.^ORCID,Pogorelov Taras V.^ORCID,Schwieters Charles D.^ORCID,Fan Timothy M.^ORCID,Rienstra Chad M.^ORCID,Burke Martin D.^ORCID

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

https://www.nature.com/articles/s41586-023-06710-4.pdf

Reference64 articles.

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3. Anderson, T. M. et al. Amphotericin forms an extramembranous and fungicidal sterol sponge. Nat. Chem. Biol. 10, 400–406 (2014).

4. Lewandowska, A. et al. Fungicidal amphotericin B sponges are assemblies of staggered asymmetric homodimers encasing large void volumes. Nat. Struct. Mol. Biol. 28, 972–981 (2021).

5. Guo, X. et al. Sterol sponge mechanism is conserved for glycosylated polyene macrolides. ACS Cent. Sci. 7, 781–791 (2021).

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