Interfering with the Tumor–Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors-Reference-Cited by-同舟云学术

Interfering with the Tumor–Immune Interface: Making Way for Triazine-Based Small Molecules as Novel PD-L1 Inhibitors

Published:2021-10-20 Issue:21 Volume:64 Page:16020-16045
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Russomanno Pasquale¹,Assoni Giulia²³,Amato Jussara¹^ORCID,D’Amore Vincenzo Maria¹,Scaglia Riccardo³,Brancaccio Diego¹,Pedrini Martina³,Polcaro Giovanna⁴,La Pietra Valeria¹,Orlando Paolo³,Falzoni Marianna³,Cerofolini Linda⁵,Giuntini Stefano⁵,Fragai Marco⁵^ORCID,Pagano Bruno¹^ORCID,Donati Greta¹,Novellino Ettore⁶^ORCID,Quintavalle Cristina⁷,Condorelli Gerolama⁷⁸,Sabbatino Francesco⁴,Seneci Pierfausto³^ORCID,Arosio Daniela⁹,Pepe Stefano⁴,Marinelli Luciana¹^ORCID

Affiliation:

1. Dipartimento di Farmacia, Università degli Studi di Napoli Federico II, Via D. Montesano 49, Napoli 80131, Italy

2. Department of Cellular, Computational and Integrative Biology, (CIBIO), Università degli Studi di Trento, Via Sommarive 9, Povo I-38123, Trento, Italy

3. Chemistry Department, Università degli Studi di Milano, Via C. Golgi 19, Milan 20133, Italy

4. Dipartimento di Medicina e Chirurgia, Ospedale “San Giovanni di Dio e Ruggi d’Aragona”, Università di Salerno, Salerno 84131, Italy

5. Centro di Risonanza Magnetica, CERM, Università di Firenze, Firenze 50019, Italy

6. Università Cattolica del Sacro Cuore, Rome 00168, Italy

7. Department of Molecular Medicine and Medical Biotechnology, “Federico II” University, Naples, Italy; Institute for Experimental Endocrinology and Oncology (IEOS), National Research Council (CNR), Naples 80131, Italy

8. Department of Molecular Medicine and Medical Biotechnology, “Federico II” University, Naples 80131, Italy

9. Istituto di Scienze e Tecnologie Chimiche “Giulio Natta” (SCITEC), Consiglio Nazionale delle Ricerche (CNR), Via C. Golgi 19, Milan 20133, Italy

Funder

H2020 Marie Sk??odowska-Curie Actions

Regione Campania

Ministero dell'Istruzione, dell'Universit?? e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01409