Relaxed Substrate Requirements of Sterol 14α-Demethylase from Naegleria fowleri Are Accompanied by Resistance to Inhibition-Reference-Cited by-同舟云学术

Relaxed Substrate Requirements of Sterol 14α-Demethylase from Naegleria fowleri Are Accompanied by Resistance to Inhibition

Author:

Hargrove Tatiana Y.¹,Wawrzak Zdzislaw²,Rachakonda Girish³,Nes W. David⁴,Villalta Fernando³,Guengerich F. Peter¹^ORCID,Lepesheva Galina I.¹⁵^ORCID

Affiliation:

1. Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, United States

2. Synchrotron Research Center, Life Science Collaborative Access Team, Northwestern University, Argonne, Illinois 60439, United States

3. Department of Microbiology, Immunology and Physiology, Meharry Medical College, Nashville, Tennessee 37208, United States

4. Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409, United States

5. Center for Structural Biology, Vanderbilt University, Nashville, Tennessee 37232, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

Reference44 articles.

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献