Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability-Reference-Cited by-同舟云学术

Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability

Published:2021-08-26 Issue:17 Volume:64 Page:12705-12722
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rahman Md. Shafikur¹,Kumari Shikha¹,Esfahani Shiva Hadi²,Nozohouri Saeideh²,Jayaraman Srinidhi²,Kinarivala Nihar²^ORCID,Kocot Joanna²,Baez Andrew²,Farris Delaney²,Abbruscato Thomas J.²³,Karamyan Vardan T.²³^ORCID,Trippier Paul C.¹⁴⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

2. Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, United States

3. Center for Blood Brain Barrier Research, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas 79106, United States

4. Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

5. UNMC Center for Drug Discovery, University of Nebraska Medical Center, Omaha, Nebraska 68198, United States

Funder

National Institute of Neurological Disorders and Stroke

University of Nebraska Medical Center

Health Sciences Center, Texas Tech University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00759

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