Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn2+ as Potent Broad-Spectrum Antibacterial Agents with a Membrane-Disruptive Mechanism-Reference-Cited by-同舟云学术

Rational Design of Dipicolylamine-Containing Carbazole Amphiphiles Combined with Zn2+ as Potent Broad-Spectrum Antibacterial Agents with a Membrane-Disruptive Mechanism

Published:2021-07-08 Issue:14 Volume:64 Page:10429-10444
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Liu Jiayong¹^ORCID,Li Hongxia¹,Li Haizhou¹,Fang Shanfang¹,Shi Jinguo²,Chen Yongzhi¹,Zhong Rongcui¹,Liu Shouping¹,Lin Shuimu¹^ORCID

Affiliation:

1. Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, P.R. China

2. Department of Medicinal Chemistry, School of Pharmaceutical Science, Sun Yat-sen University, Guangzhou 510006, P. R. China

Funder

National Natural Science Foundation of China

Talent Fund for High-Level University Construction of Guangzhou

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00858

Reference70 articles.

1. Evolution of MRSA During Hospital Transmission and Intercontinental Spread