Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity-Reference-Cited by-同舟云学术

Development of Potent and Selective Agonists for Complement C5a Receptor 1 with In Vivo Activity

Published:2021-11-11 Issue:22 Volume:64 Page:16598-16608
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Gorman Declan M.¹,Li Xaria X.¹,Lee John D.¹,Fung Jenny N.¹,Cui Cedric S.¹,Lee Han Siean¹,Rolfe Barbara E.²^ORCID,Woodruff Trent M.¹³^ORCID,Clark Richard J.¹^ORCID

Affiliation:

1. School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland 4072, Australia

2. Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, Brisbane, Queensland 4072, Australia

3. Queensland Brain Institute, The University of Queensland, Brisbane, Queensland 4072, Australia

Funder

National Health and Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01174

Reference55 articles.

1. THE REACTION MECHANISM OF HUMAN C5 IN IMMUNE HEMOLYSIS

2. Complement component 5a (C5a)

3. Partial ligand-receptor engagement yields functional bias at the human complement receptor, C5aR1

4. Expression cloning of a receptor for C5a anaphylatoxin on differentiated HL-60 cells

5. Expression and Function of C5a Receptor in Mouse Microvascular Endothelial Cells

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity;Bone Research;2024-01-24

2. Chemical synthesis of grafted cyclotides using a “plug and play” approach;RSC Chemical Biology;2024

3. The role of the complement system in cancer etiology and management;Clinical Immuno-Oncology;2024

4. Functional profiling of the G protein-coupled receptor C3aR1 reveals ligand-mediated biased agonism;Journal of Biological Chemistry;2024-01

5. Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation;STAR Protocols;2023-12