Chemical synthesis of grafted cyclotides using a “plug and play” approach-Reference-Cited by-同舟云学术

Chemical synthesis of grafted cyclotides using a “plug and play” approach

Published:2024 Issue:6 Volume:5 Page:567-571
ISSN:2633-0679
Container-title:RSC Chemical Biology
language:en
Short-container-title:RSC Chem. Biol.

Author:

Koehbach Johannes¹²^ORCID,Muratspahić Edin³,Ahmed Zakaria M²,White Andrew M¹⁴^ORCID,Tomašević Nataša³,Durek Thomas¹,Clark Richard J²^ORCID,Gruber Christian W³^ORCID,Craik David J¹^ORCID

Affiliation:

1. Institute for Molecular Bioscience, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Queensland, Brisbane, Queensland, Australia

2. School of Biomedical Sciences, The University of Queensland, Brisbane, Queensland, Australia

3. Center for Physiology and Pharmacology, Institute of Pharmacology, Medical University of Vienna, Vienna, Austria

4. Research School of Chemistry, Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, Australian National University, Australia

Abstract

‘Plug and play’ grafting – a simple and convenient modular synthesis method to access complex cyclotide grafts and generate potent GPCR ligands is described.

Funder

National Health and Medical Research Council

Austrian Science Fund

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CB/D4CB00008K

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