Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells-Reference-Cited by-同舟云学术

Proteolysis-Targeting Chimera (PROTAC) Modification of Dovitinib Enhances the Antiproliferative Effect against FLT3-ITD-Positive Acute Myeloid Leukemia Cells

Published:2021-10-25 Issue:22 Volume:64 Page:16497-16511
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Cao Sheng¹^ORCID,Ma Lan¹²,Liu Yulin¹,Wei Mingming¹,Yao Yuhong¹,Li Chen¹^ORCID,Wang Ruonan¹,Liu Ning¹,Dong Zhiqiang¹²,Li Xuechun¹²,Li Ming³,Wang Xiaoji⁴,Yang Cheng¹,Yang Guang¹^ORCID

Affiliation:

1. The State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300071, P. R. China

2. Tianjin International Joint Academy of Biomedicine, Tianjin 300457, P. R. China

3. Cangzhou Institutes for Food and Drug Control, Cangzhou 061000, P. R. China

4. Engineering Research Center of Health Food Design & Nutrition Regulation, School of Chemical Engineering and Energy Technology, Dongguan University of Technology, Dongguan 523808, Guangdong Province, P. R. China

Funder

Ningbo Municipal Bureau of Science and Technology

National Natural Science Foundation of China

Key research program directing project of Cangzhou City

Key Research and Development Program of Tianjin City

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c00996

Reference30 articles.