G-749, a novel FLT3 kinase inhibitor, can overcome drug resistance for the treatment of acute myeloid leukemia
Author:
Affiliation:
1. Oscotec Inc., Gyeonggi-do, Republic of Korea;
2. Genosco, Cambridge, MA; and
3. Center for the Biology of Disease, VIB, Leuven, Belgium
Abstract
Publisher
American Society of Hematology
Subject
Cell Biology,Hematology,Immunology,Biochemistry
Link
http://ashpublications.org/blood/article-pdf/123/14/2209/1375250/2209.pdf
Reference42 articles.
1. The role of FLT3 in haematopoietic malignancies.;Stirewalt;Nat Rev Cancer,2003
2. Internal tandem duplication of the flt3 gene found in acute myeloid leukemia.;Nakao;Leukemia,1996
3. Tandem duplications of the FLT3 receptor gene are associated with leukemic transformation of myelodysplasia.;Horiike;Leukemia,1997
4. Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.;Yamamoto;Blood,2001
5. Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia.;Kornblau;Blood,2006
Cited by 44 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Annual review of PROTAC degraders as anticancer agents in 2022;European Journal of Medicinal Chemistry;2024-03
2. Update on Small Molecule Targeted Therapies for Acute Myeloid Leukemia;Current Treatment Options in Oncology;2023-05-17
3. Next-Generation FLT3 Inhibitors for the Treatment of FLT3-Positive AML;Pathogenesis and Treatment of Leukemia;2023
4. Small molecule inhibitors targeting the cancers;MedComm;2022-10-13
5. PROTACs: great opportunities for academia and industry (an update from 2020 to 2021);Signal Transduction and Targeted Therapy;2022-06-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3