Discovery of Potent Isoquinolinequinone <i>N</i>-Oxides to Overcome Cancer Multidrug Resistance-Reference-Cited by-同舟云学术

Discovery of Potent Isoquinolinequinone N-Oxides to Overcome Cancer Multidrug Resistance

Published:2024-08-02 Issue:16 Volume:67 Page:13909-13924
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kruschel Ryan D.¹^ORCID,Barbosa Mélanie A. G.²³⁴^ORCID,Almeida Maria João²³^ORCID,Xavier Cristina P. R.²³^ORCID,Vasconcelos M. Helena²³⁴^ORCID,McCarthy Florence O.¹^ORCID

Affiliation:

1. School of Chemistry, Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 K8AF, Ireland

2. i3S−Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto Portugal

3. Cancer Drug Resistance Group, IPATIMUP−Institute of Molecular Pathology and Immunology, University of Porto, 4200-135 Porto Portugal

4. FFUP−Faculty of Pharmacy of the University of Porto, 4050-313 Porto Portugal

Funder

Irish Research Council

European Commission

European Cooperation in Science and Technology

ComissÃ£o de CoordenaÃ§Ã£o e Desenvolvimento Regional do Norte

MinistÃ©rio da EducaÃ§Ã£o e CiÃªncia

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00705

Reference82 articles.

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3. Targeting multidrug resistance in cancer

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5. Structure–Activity Relationships of 8-Hydroxyquinoline-Derived Mannich Bases with Tertiary Amines Targeting Multidrug-Resistant Cancer