Ocotillol Derivatives Mitigate Retinal Ischemia-Reperfusion Injury by Regulating the Keap1/Nrf2/ARE Signaling Pathway-Reference-Cited by-同舟云学术

Ocotillol Derivatives Mitigate Retinal Ischemia-Reperfusion Injury by Regulating the Keap1/Nrf2/ARE Signaling Pathway

Published:2024-08-15 Issue:17 Volume:67 Page:15268-15290
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Xin¹,Zhang Wen¹,Zhao Laien¹,Ma Gongshan¹,Huang Yanmei¹,Geng Zhiyuan¹,Jiang Qian¹,Wen Xiaomei¹,Lin Yuqi¹,Meng Qingguo¹,Zhang Zhuhong¹,Bi Yi¹^ORCID

Affiliation:

1. School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai 264005, PR China

Funder

Taishan Scholar Project of Shandong Province

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

College Students Innovation and Entrepreneurship Training Program

Yantai Science and Technology Innovation Development Plan

The Science and Technology Support Program for Youth Innovation in Universities of Shandong

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.4c00867

Reference62 articles.

1. Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury

2. Simvastatin inhibits ischemia/reperfusion injury-induced apoptosis of retinal cells via downregulation of the tumor necrosis factor-α/nuclear factor-κB pathway

3. Inhibition of the Keap1-Nrf2 protein-protein interaction protects retinal cells and ameliorates retinal ischemia-reperfusion injury

4. Cellular Stress Response and Immune Signaling in Retinal Ischemia–Reperfusion Injury

5. Neuroprotective role of Nrf2 for retinal ganglion cells in ischemia-reperfusion