Coupling a Virulence-Targeting Moiety with Ru-Based AMP Mimics Efficiently Improved Its Anti-Infective Potency and Therapeutic Index-Reference-Cited by-同舟云学术

Coupling a Virulence-Targeting Moiety with Ru-Based AMP Mimics Efficiently Improved Its Anti-Infective Potency and Therapeutic Index

Published:2023-09-13 Issue:18 Volume:66 Page:13304-13318
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wang Jing¹,Song Yun¹,Huang Ziying¹,Lin Wenjing¹,Yu Guangying¹,Xiong Yanshi¹,Jiang Guijuan¹,Tan Yanhui²,Wang Jintao¹^ORCID,Liao Xiangwen¹^ORCID

Affiliation:

1. Jiangxi Provincial Key Laboratory of Drug Design and Evaluation, School of Pharmacy, Jiangxi Science & Technology Normal University, Nanchang 330013, China

2. State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China

Funder

Jiangxi Normal University

Jiangxi Provincial Department of Science and Technology

National Natural Science Foundation of China

Natural Science Foundation of Jiangxi Province

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01282

Reference61 articles.