Tackling the threat of antimicrobial resistance: from policy to sustainable action

Author:

Shallcross Laura J.12,Howard Simon J.3,Fowler Tom45,Davies Sally C.1

Affiliation:

1. Department of Health, Office of the Chief Medical Officer, 79 Whitehall, London SW1A 2NS, UK

2. Research Department of Infection and Population Health, University College London, 222 Euston Road, London NW1 2DA, UK

3. North East Health Protection Team, Public Health England, Gallowgate, Newcastle-upon-Tyne NE1 4WH, UK

4. Genomics England, Queen Mary University of London, Dawson Hall, Charterhouse Square, London EC1M 6BQ, UK

5. Public Health, Epidemiology and Biostatistics, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

Abstract

Antibiotics underpin all of modern medicine, from routine major surgery through to caesarean sections and modern cancer therapies. These drugs have revolutionized how we practice medicine, but we are in a constant evolutionary battle to evade microbial resistance and this has become a major global public health problem. We have overused and misused these essential medicines both in the human and animal health sectors and this threatens the effectiveness of antimicrobials for future generations. We can only address the threat of antimicrobial resistance (AMR) through international collaboration across human and animal health sectors integrating social, economic and behavioural factors. Our global organizations are rising to the challenge with the recent World Health Assembly resolution on AMR and development of the Global Action plan but we must act now to avoid a return to a pre-antibiotic era.

Publisher

The Royal Society

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

Reference18 articles.

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2. World Health Organization. The top 10 causes of death . http://www.who.int/mediacentre/factsheets/fs310/en/index1.html (accessed 15 January 2015).

3. Challenges of Antibacterial Discovery

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